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Open Positions

POC INSTRUMENT - Proof of concept by Campagnia di San Paolo

2023
3VS: Prototyping and validation of a vesicular nanotechnological device for gene therapy alternative to viral vectors. This project was based on the patent “Method for obtaining concentrated populations of extracellular vesicles (EVs) washed of physiopathological load thereof”, WO2023/073609A1. The aim of the project was the encapsulation of a plasmid DNA inside lymphocytes-derived EVs, osmotically lysed using the method described in the patent. The efficacy and safety of this new vesicular viral vector substitute was compared with more traditional methods of gene transfer such as non-liposomal lipids and lentiviral vectors for the treatment of multiple myeloma.
FRAMEWORK
Campagnia di San Paolo
PARTNERS
Molecular Biology Center (MBC) of University of Turin, CNR of Turin

other projects

RECYCLE-CO2 - A Combined Experimental and Theoretical Approach for Single-Atom Catalyst Engineering Towards Tuneable Activity and Selectivity in CO2 electroreduction
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ECOMATES - Electrochemical conversion of CO2 into added value products via highly selective bimetallic MATerials and innovative process dESig
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Centro Nazionale di Ricerca in High Performance Computing, Big Data e Quantum Computing
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2D-EMMA - Technologically Scalable 2D Materials and Extended Operando Measurement Methodologies for Advanced Device Fabrication
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ORIGAMI - Mimicking in vivo-like tumor microenvironment to model non-small cell lung cancer patient-derived organoids dynamics
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MICS - Made in Italy Circolare e Sostenibile
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We firmly believe that one of the Group’s strengths lies in the transdisciplinary approach that stems from active collaboration between experts from different fields, crucial for achieving results in both research and technological transfer.
RESEARCH ACTIVITIES